According to the results of a recent research it has been found that there is a chemical that might help in improving the memory.
This chemical is known as Methylene Blue and according to the research it has been found that it results in increase in response in the brain areas which control the short-term memory.
The researchers have concluded that as per their findings a single dose of this very common as well as inexpensive and safe chemical that is known as methylene blue has resulted in an increased response in the brain areas that control our short term memory as well as the attention.
The new research has also hinted upon certain new findings such as – a single dose taken orally of a drug which is already being used for treating a certain type of a blood disorder could also contribute towards improving our memory. The said chemical that is Methylene blue is also being used for treating methemoglobinemia which is a kind of a blood disorder. In methemoglobinemia oxygen is unable to release effectively to the body tissues and as a surgical stain.
Timothy Duong who is the study’s author from the University of Texas Health Science Center at San Antonio, Texas said in a statement that even though, the memory-enhancing effects that methylene blue has were seen in rodents in the 1970s, but the underlying neuronal changes in the brain which are responsible for our memory improvement and the effects that methylene blue has on our short-term memory and sustained-attention tasks have not been investigated. Also, Timothy Duong added to his statement that our team decided to conduct the first multi-modal MRI study of methylene blue in humans.
Participants of ages between twenty two and sixty two were signed up into a double-blinded, randomized, placebo-controlled clinical trial. There were total twenty participants in number. This trial was done in order to measure the effects of methylene blue on the human brain during sustained-attention task as well as in working-memory.
One hour before and one hour after low-dose methylene blue or placebo administration all the participants had gone through functional MRI (FMRI) done to analyze the possible effects of the compound on cerebrovascular reactivity during the tasks. And pre as well as post the intervention the mean cerebral blood flow was measured.
The results came out showing that methylene blue had increased the response in the bilateral insular cortex —which is an area deep within the brain and it is associated with the emotional responses — during a task that measured reaction time to a visual stimulus.
Results of the functional MRI also showed that there was an increased response during short-term memory tasks that involve the brain’s prefrontal cortex which is primarily associated with the processing of sensory information as well as the occipital cortex that is the visual processing center of the brain.
In addition, methylene blue was associated with a seven percent increase in correct responses during memory retrieval.